Lumi-Aggregation Performed in up to four (4) PRP or Whole Blood Samples
The CHRONO-LOG® Model 700 Whole Blood/Optical Lumi-Aggregometers are available
in a two or four channel configuration. This state-of-the-art Lumi-Aggregometer measures platelet
function on patient samples using electrical impedance in whole blood samples or optical
density in plasma with the simultaneous measurement ATP Release by the luminescence
method. The Model 700 Lumi-Aggregometer also has the capability of performing the
for diagnosing patients with von Willebrand's disease. The output
can be connected to either a strip chart recorder or to a Computer. AGGRO/LINK®8
and vW Cofactor Software packages are provided for the computer interface option.
With a proven track record of providing accurate and reliable results, the Chrono-log
Whole Blood/Optical Lumi-Aggregometer is both a reliable diagnostic tool and a comprehensive
screening tool. Direct measurement of ATP secretion during platelet aggregation
provides unequivocal evidence of normal dense granule release. The simultaneous measurement
of Aggregation and dense granule release provides a better insight into the mechanism
of platelet response.
The Model 700 Whole Blood/Optical Lumi-Aggregometer available Housed in a smaller
chassis, the Model 700 Aggregometer is available in configurations of up to Four
(4) channels of aggregation and luminescence. The Baseline and Gain are set with
a single Pushbutton. The front panel has a 24 character Liquid Crystal Display (LCD)
for each channel. The heater block temperature, the luminescence gain, the stirring
speed and the operating mode (Optical or Impedance) as well as warning messages
are displayed on the front panel LCD. The instrument has the ability to use Disposable or Reusable Electrodes
for Impedance Aggregation.
Included with the Model 700 are software programs for platelet aggregation and the
ristocetin cofactor assay. The AGGRO/LINK®8 program provides real time color display
of up to four (4) channels of aggregation and ATP release, displaying a total of eight (8)
traces. This program performs computation of the traces reporting the results as
maximum amplitude and slope. Lag time and
area under the curve analysis are also
available for each trace. Each graph, its values, patient demographics and reagent
information are then stored on computer disk for later retrieval and printing. Test
graphs can be easily recalled for viewing or printing, while data points can be copied to Excel.
The CHRONO-LOG® von Willebrand Cofactor software package simplifies the vW assay. On-screen
instructions guide the operator through the procedures to run dilutions for the
standard curve and to test patient samples. The best-fit standard curve
automatically and then stored along with reagent lot numbers. Up to four (4) samples
can be processed simultaneously; tests on samples need not start and stop at the
same time, allowing for stress-free operation. Percent activity
is automatically calculated and reported.
Please call 1-800-247-6665 or
us, to obtain information on the CHRONO-LOG® Whole Blood Aggregation
Assays or to purchase a CHRONO-LOG® Model 700.