Chrono-log's wide range of Platelet Aggregometers allows you to choose the instrument with the capabilities to meet your particular needs. Chrono-log models have single, dual, four and eight sample units, and are available with chart recorder outputs or digital computer outputs. CHRONO-LOG^® Platelet Aggregation Systems provide the following platelet testing options:

OPTICAL AGGREGOMETERS: Measure platelet aggregation in platelet-rich-plasma (PRP), using the Light Transmission method developed by Born.

The Model 490 4+4 provides four (4) or eight (8) test channels for testing PRP, Washed or Gel-Filtered platelet samples.

LUMI-AGGREGOMETERS: Simultaneously measure aggregation and ATP secretion in the same sample, to provide a quantitative determination of second wave aggregation and to simplify the diagnosis of storage pool defects and the effects of aspirin-like drugs.

The Model 700 Aggregometer provides up to four (4) channels of platelet aggregation in either whole blood or PRP with simultaneous measurement of secretion.

WHOLE BLOOD AGGREGOMETERS: Measure aggregation directly in whole blood, a more physiological milieu than PRP; requires less patient blood (0.5 mL/test vs. 2.0 mL/test for PRP), reduces labor costs and improves turn-around time for a complete panel (less than 30 minutes in whole blood, 1.5 to 3 hours in PRP). The advantages of the Whole Blood Aggregometers have been well documented in the peer-reviewed literature, as well as by many laboratory directors. Studies have shown that whole blood aggregation yields information similar to optical aggregation in PRP.

Whole blood aggregation is ideal for testing the effects of anti-platelet drugs on platelet function, since platelets are tested in their natural environment. Ease of operation, with automatic setting of baseline and gain and the elimination of sample manipulation, makes it feasible for platelet aggregation to be tested cost effectively in laboratories of any size. User training time is also reduced, resulting in additional cost savings.

Whole blood aggregation is valuable when you must have a rapid, reliable and cost-effective screen to detect specific platelet abnormalities.

To see how the whole blood aggregation meets your platelet function testing needs quickly, accurately and affordably - click here.

CHRONO-LOG^® Platelet Aggregation Systems are currently in use for the clinical diagnosis of platelet disorders and monitoring the effects of drugs on platelet function. They are also used to study Heparin-Induced Thrombocytopenia (HIT) , leukocyte and neutrophil aggregation, and for the measurement of superoxides and free radicals.

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