[vc_row content_placement=”middle” woodmart_css_id=”6903c3cdbadff” responsive_spacing=”eyJwYXJhbV90eXBlIjoid29vZG1hcnRfcmVzcG9uc2l2ZV9zcGFjaW5nIiwic2VsZWN0b3JfaWQiOiI2OTAzYzNjZGJhZGZmIiwic2hvcnRjb2RlIjoidmNfcm93IiwiZGF0YSI6eyJ0YWJsZXQiOnt9LCJtb2JpbGUiOnt9fX0=” mobile_bg_img_hidden=”no” tablet_bg_img_hidden=”no” woodmart_parallax=”0″ woodmart_gradient_switch=”no” woodmart_box_shadow=”no” wd_z_index=”no” woodmart_disable_overflow=”0″ row_reverse_mobile=”0″ row_reverse_tablet=”0″ el_class=”inner-sec” css=”.vc_custom_1761854419968{margin-top: 30px !important;}”][vc_column width=”1/2″][woodmart_title align=”left” size=”large” font_weight=”700″ tag=”h2″ woodmart_css_id=”6a2af9b0e0e93″ title=”CHRONO-LOG® Model 490 4+4″ title_custom_color=”eyJwYXJhbV90eXBlIjoid29vZG1hcnRfY29sb3JwaWNrZXIiLCJjc3NfYXJncyI6eyJjb2xvciI6WyIgLndvb2RtYXJ0LXRpdGxlLWNvbnRhaW5lciJdfSwic2VsZWN0b3JfaWQiOiI2YTJhZjliMGUwZTkzIiwiZGF0YSI6eyJkZXNrdG9wIjoiIzAwMDAwMCJ9fQ==” responsive_spacing=”eyJwYXJhbV90eXBlIjoid29vZG1hcnRfcmVzcG9uc2l2ZV9zcGFjaW5nIiwic2VsZWN0b3JfaWQiOiI2YTJhZjliMGUwZTkzIiwic2hvcnRjb2RlIjoid29vZG1hcnRfdGl0bGUiLCJkYXRhIjp7InRhYmxldCI6e30sIm1vYmlsZSI6e319fQ==” wd_hide_on_desktop=”no” wd_hide_on_tablet=”no” wd_hide_on_mobile=”no”][woodmart_text_block text_font_family=”primary” text_font_size=”s” text_font_weight=”500″ text_color=”custom” woodmart_css_id=”6a4eb2647eed0″ woodmart_inline=”no” responsive_spacing=”eyJwYXJhbV90eXBlIjoid29vZG1hcnRfcmVzcG9uc2l2ZV9zcGFjaW5nIiwic2VsZWN0b3JfaWQiOiI2YTRlYjI2NDdlZWQwIiwic2hvcnRjb2RlIjoid29vZG1hcnRfdGV4dF9ibG9jayIsImRhdGEiOnsidGFibGV0Ijp7fSwibW9iaWxlIjp7fX19″ parallax_scroll=”no” wd_hide_on_desktop=”no” wd_hide_on_tablet=”no” wd_hide_on_mobile=”no” text_color_custom=”eyJwYXJhbV90eXBlIjoid29vZG1hcnRfY29sb3JwaWNrZXIiLCJjc3NfYXJncyI6eyJjb2xvciI6WyIud2QtdGV4dC1ibG9jayJdfSwic2VsZWN0b3JfaWQiOiI2YTRlYjI2NDdlZWQwIiwiZGF0YSI6eyJkZXNrdG9wIjoiIzY1NjU2NSJ9fQ==”]The Model 490 4+4 is a semi-automated Light Transmittance Aggregometer designed for testing in platelet aggregation studies.
Available in four or eight configurations (via two integrated modules), the CHRONO-LOG® Model 490 4+4 Optical Aggregometer provides advanced measurement of platelet function in plasma samples while offering flexible throughput tailored to diverse laboratory needs.
Utilizing an infrared light source and photo-diode detectors, the Model 490 4+4 accurately measures light transmittance differences between platelet-rich plasma (PRP) and platelet-poor plasma (PPP) channels. This advanced optical design ensures reliable and reproducible results.
The system is complemented by a complete line of reagents optimized for micro-volume testing, providing laboratories with high accuracy while maintaining a low cost per test—ideal for both research and routine clinical use.[/woodmart_text_block][/vc_column][vc_column width=”1/2″]
1. Key Features
- Optical Aggregation Test Modes for PRP and washed platelets
- Channel Configuration:
Four or eight independently operated test channels
Over-range detection prevents operation without baseline set - Display & Monitoring:
LCD display for each channel
Internal error monitoring - Calibration:
Automatic calibration for Optical Aggregation - Software:
AGGRO/LINK® Opti8
vW Cofactor Opti8 software package
2. Technical Specifications
Sample Volumes
- Optical Aggregation:
500 μL PRP or 250 μL PRP - vWF Cofactor Assay:
400 μLPlatelets or 200 μLPlatelets
General Specifications (Per Module)
- Power Requirements:
Switch-selectable 115 or 230 VAC (±10%), 50/60 Hz, 60 watts max. - Dimensions:
14″ (35.5 cm) W × 8.5″ (21.6 cm) H × 15″ (38 cm) D - Weight:
19.3 lbs. (8.75 kg) - Incubation Wells:
Two (2) wells per channel @ 36.5°C ± 1.0°C (set at 37°C) - Operating Environment:
22°C–40°C (68°F–95°F)
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3. Assays
Clinical Assays
- Optical Platelet Aggregation
- Ristocetin-Induced Platelet Aggregation
- VWF Ristocetin Cofactor Activity
- Antiplatelet Drug Response
- Heparin-Induced Thrombocytopenia (HIT) Detection
Platelet Research Applications
- Pharmaceutical Research
- Leukocyte Aggregation
- Studies with PRP, washed, or gel-filtered platelets
- Antiplatelet Drug Response
4.Consumables & Reagents
- P/N 311 Stir Bars for P/N 312 Cuvettes (144/pkg) 311
- P/N 312 Optical Cuvettes, glass (144/pkg)
- P/N 384 ADP, 5 mL
- P/N 385 Collagen, 1 mL
- P/N 386 Thrombin, 1 mL
- P/N 387 ATP Standard, 5 mL
- P/N 390 Arachidonic Acid, 0.7 mL
- P/N 393 Epinephrine, 5 mL
- P/N 396 Ristocetin (for RIPA), 0.5 mL
- P/N 299 Ristocetin Cofactor Assay Kit, 15 Determinations (299-6 & 299-7 Not Included)
- P/N 299-1 Ristocetin (7.5 mg/mL), 0.75 mL
- P/N 299-2 Lyophilized Human Platelets, 6 mL & P/N 299-5 Tris-Buffered Saline, 12 mL
- P/N 299-3 vW Reference Plasma Normal, 1 mL
- P/N 299-4 vW Reference Plasma Deficient, 0.5 mL
- P/N 299-5 Tris-Buffered Saline, 12 mL
- P/N 299-6 Hemostasis Reference Plasma Normal, 1 mL
- P/N 299-7 Hemostasis Reference Plasma Abnormal, 1 mL
5. Downloads
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